Indice degli argomenti
Introduzione
Introduction
TOX-OER MOOC (Massive Online Open Courses) is a free pedagogical platform to deliver and share knowledge and skills related to the toxicology field by seven European countries. Our objective is to improve the access of learning in toxicology, the active learning, the virtual and blended mobility.
You can join to the TOX-OER courses in modular or sequential way. It depends by your interest and background.
Module 1
This module aims to define Toxicology and its main areas (Mechanistic, Descriptive and Regulatory). The sub-disciplines Forensic, Clinical, Environmental, Occupational Toxicology as well as Toxicogenomics will be also presented in video. Concepts of toxic, toxin, xenobiotics, types of intoxications (acute/chronic, accidental/intentional), types of xenobiotic interactions (additive, synergic, potentiation and antagonism), tolerance, maximum effect and potency will be explain.
Course link:
Module 2
This module aims to describe the phenomena of pharmaco-toxicokinetic and contextualize the pharmacological and toxicological consequences related to the absorption, distribution, metabolism, excretion and transport (ADMET) of xenobiotics (drugs and toxic compounds). The students will contact with movies showing the ADMET processes as well as research data that will allow them to interpret the risks associated with xenobiotic exposure related to their disposition in the organism.
Course link:
http://moodle.toxoer.com/course/index.php?categoryid=5
Module 3
This module describes the main toxicological characteristics of prescription and abuse drugs, and their differences from legal and scientific points of view. Analytical methods for their qualitative and quantitative determination in different biological and non-biological matrices will be described and discussed. The most important aspects of regulations in the pharmaceutical sector will be provided and explained.
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Module 4
The aim of this module is to describe the impact of some pollutants (gaseous pollutants, persistent organic pollutants, heavy metals and pesticides) on the human health, as well as on the environment.
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Module 5
This module aims to learn the adverse effects or pathological states caused by toxicants in specific organs of the body.
For each organ, several aspects will be discussed: the main mechanisms involved in the toxicity, the main toxicants responsible for the damage and the currently used biomarkers which are able to specify the kind of damage and the place where is being produced.
Course link:
http://moodle.toxoer.com/course/index.php?categoryid=8
Module 6
The goal of the module is to understand the correlation between the sources of toxic emissions and the assessment systems of emissions and immissions, according to personal and authoritative rights and duties related to toxic pollutants. The content and activities are discussed based on the pollutants’ flow: source – transport – targeted environmental components.
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Module 7
This module aims to provide basic information about the patent system and when an invention can be patentable. Concepts about patentability will be dealt with and several examples about patents in the chemistry field will be provided. The enforcement of patent rights will be also discussed.
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Gamification ideas
In order to sustain the active learning within an online scenario, this section presents several ideas and prototype developed in the framework of TOX-OER project.
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